Vielhauer W, Eckardt V, Holtermüller K H, Lüth J B, Schulte B, Prellwitz W, Sonntag W
Dig Dis Sci. 1982 Dec;27(12):1126-9. doi: 10.1007/BF01391452.
Wilson's disease in a young woman presenting with an acute course is described. The clinical manifestations were fulminant hepatic failure associated with marked intravascular hemolysis. Immediate D-penicillamine and high-dose steroid therapy did not influence the course of the disease. Necropsy revealed an increased hepatic copper content and cirrhosis with extensive necrosis of the liver.
本文描述了一名年轻女性患威尔逊氏病且病程呈急性的情况。临床表现为暴发性肝衰竭并伴有明显的血管内溶血。立即给予青霉胺和大剂量类固醇治疗并未影响疾病进程。尸检显示肝脏铜含量增加以及伴有广泛肝坏死的肝硬化。
