Hedner T, Iversen K, Lundborg P
Early Hum Dev. 1982 Oct;7(1):53-8. doi: 10.1016/0378-3782(82)90007-x.
gamma-Aminobutyric acid (GABA) concentrations in cerebrospinal fluid (CSF) were measured in 20 neonates with various gestational and postnatal ages. These concentrations varied between 9 and 45 nmol/ml which is approximately 20-100 times the concentrations found in adults. CSF GABA concentrations tended to decrease with advancing gestational age. No apparent alterations were noted with increasing postnatal age (until 6 weeks of age). Asphyxia but not neonatal sepsis was accompanied by an increase in CSF GABA concentrations compared to respective controls.
对20名不同孕周和出生后年龄的新生儿的脑脊液（CSF）中的γ-氨基丁酸（GABA）浓度进行了测量。这些浓度在9至45纳摩尔/毫升之间变化，约为成人浓度的20至100倍。脑脊液GABA浓度倾向于随着孕周增加而降低。随着出生后年龄增加（直至6周龄）未观察到明显变化。与各自的对照组相比，窒息而非新生儿败血症伴随着脑脊液GABA浓度的升高。
