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用铊-201进行闪烁扫描以检测甲状腺癌转移灶。

Scintigraphy with 201Tl for detection of thyroid cancer metastases.

作者信息

Piers D A, Sluiter W J, Willemse P H, Doorenbos H

出版信息

Eur J Nucl Med. 1982;7(11):515-7. doi: 10.1007/BF00257220.

DOI:10.1007/BF00257220
PMID:7173250
Abstract

In four patients with disseminated papillary or follicular thyroid carcinoma metastatic sites could be demonstrated by scintigraphy with 201Tl. Uptake was present during TSH suppression with thyroid hormone administration. In three of the four cases 201Tl scanning revealed metastases while 131I uptake after triiodothyronine withdrawal was absent. In one patient 201Tl demonstrated some metastatic sites while both 131I uptake and thyroglobulin levels were negative. Uptake of 201Tl in these metastases is at least partially, unrelated to the TSH and thyroglobulin levels or to the 131I-accumulating capacity. Scintigraphy using 201Tl might be helpful for the detection of metastatic thyroid carcinoma in those cases where 131I uptake is absent.

摘要

在4例播散性乳头状或滤泡状甲状腺癌患者中,通过201Tl闪烁扫描可显示转移灶。在给予甲状腺激素抑制促甲状腺激素(TSH)期间有摄取。4例中的3例,201Tl扫描显示有转移灶,而在停用三碘甲状腺原氨酸后131I摄取缺如。1例患者201Tl显示出一些转移灶,而131I摄取和甲状腺球蛋白水平均为阴性。这些转移灶中201Tl的摄取至少部分与TSH、甲状腺球蛋白水平或131I聚集能力无关。在131I摄取缺如的情况下,使用201Tl进行闪烁扫描可能有助于检测转移性甲状腺癌。

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引用本文的文献

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World J Surg. 1984 Dec;8(6):956-62. doi: 10.1007/BF01656038.

本文引用的文献

1
Serum thyroglobulin levels predict total body iodine scan findings in patients with treated well-differentiated thyroid carcinoma.血清甲状腺球蛋白水平可预测接受治疗的分化型甲状腺癌患者的全身碘扫描结果。
Am J Med. 1980 Sep;69(3):401-7. doi: 10.1016/0002-9343(80)90011-x.
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Scintigraphic evaluation and dynamic studies with thallium-201 in thyroid lesions with suspected cancer.
Eur J Nucl Med. 1981;6(7):295-300. doi: 10.1007/BF00262523.
3
Papillary thyroid carcinoma: a 10 year follow-up report of the impact of therapy in 576 patients.甲状腺乳头状癌:576例患者治疗效果的10年随访报告
Am J Med. 1981 Mar;70(3):511-8. doi: 10.1016/0002-9343(81)90573-8.
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Thyroid uptake of 201thallium and its control by TSH.201铊的甲状腺摄取及其受促甲状腺激素的调控
Acta Endocrinol (Copenh). 1981 Aug;97(4):461-5. doi: 10.1530/acta.0.0970461.
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Radiology. 1976 Nov;121(2):487-8. doi: 10.1148/121.2.487.
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Thallium-201 for medical use. Part 3: Human distribution and physical imaging properties.医用铊 - 201。第3部分:人体分布及物理成像特性。
J Nucl Med. 1977 Feb;18(2):133-40.
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The value of thallium-201 imaging in the diagnosis of thyroid carcinoma in a patient with negative 99mTc and 131I scans.
Clin Nucl Med. 1978 Nov;3(11):447-8. doi: 10.1097/00003072-197811000-00012.
10
Clinical application of 201Tl scintigraphy in patients with cold thyroid nodules.
Clin Nucl Med. 1978 Jun;3(6):217-21. doi: 10.1097/00003072-197806000-00004.