Piers D A, Sluiter W J, Willemse P H, Doorenbos H
Eur J Nucl Med. 1982;7(11):515-7. doi: 10.1007/BF00257220.
In four patients with disseminated papillary or follicular thyroid carcinoma metastatic sites could be demonstrated by scintigraphy with 201Tl. Uptake was present during TSH suppression with thyroid hormone administration. In three of the four cases 201Tl scanning revealed metastases while 131I uptake after triiodothyronine withdrawal was absent. In one patient 201Tl demonstrated some metastatic sites while both 131I uptake and thyroglobulin levels were negative. Uptake of 201Tl in these metastases is at least partially, unrelated to the TSH and thyroglobulin levels or to the 131I-accumulating capacity. Scintigraphy using 201Tl might be helpful for the detection of metastatic thyroid carcinoma in those cases where 131I uptake is absent.
在4例播散性乳头状或滤泡状甲状腺癌患者中,通过201Tl闪烁扫描可显示转移灶。在给予甲状腺激素抑制促甲状腺激素(TSH)期间有摄取。4例中的3例,201Tl扫描显示有转移灶,而在停用三碘甲状腺原氨酸后131I摄取缺如。1例患者201Tl显示出一些转移灶,而131I摄取和甲状腺球蛋白水平均为阴性。这些转移灶中201Tl的摄取至少部分与TSH、甲状腺球蛋白水平或131I聚集能力无关。在131I摄取缺如的情况下,使用201Tl进行闪烁扫描可能有助于检测转移性甲状腺癌。