Rauschecker J P
Exp Brain Res. 1982;48(2):301-5. doi: 10.1007/BF00237227.
Kittens were reared wearing masks that contained strong cylindrical lenses, which allowed them to see only contours of one orientation. Selective exposure was alternated between the two eyes on successive days, while each time the other eye was covered by the mask. The total duration of exposure was different in the two eyes, amounting to 50 h for one eye and at least 100 h for the other. This resulted in asymmetric distributions of ocular dominance: neurones preferring precisely the experienced orientation favoured the eye with longer exposure, whereas neurones preferring oblique orientations adjacent to the experienced one surprisingly were dominated by the eye with shorter exposure. Thus neurones originally belonging to this group and dominated by the longer exposed eye must have tuned their orientation preference to the experienced orientation as a result of the longer exposure. Such instructive changes seem to be limited by the original response borders of the cortical neurones, as predicted by Hebb's rules for synaptic plasticity.
小猫在佩戴含有强柱面透镜的面罩的情况下饲养，这使得它们只能看到一个方向的轮廓。在连续的日子里，选择性暴露在两只眼睛之间交替进行，每次另一只眼睛被面罩遮住。两只眼睛的总暴露时间不同，一只眼睛为50小时，另一只眼睛至少为100小时。这导致了眼优势的不对称分布：精确偏好经历过的方向的神经元更倾向于暴露时间较长的眼睛，而令人惊讶的是，偏好与经历过的方向相邻的倾斜方向的神经元则由暴露时间较短的眼睛主导。因此，原本属于这一组且由暴露时间较长的眼睛主导的神经元，必然是由于较长时间的暴露而将其方向偏好调整为经历过的方向。正如赫布突触可塑性规则所预测的那样，这种指导性变化似乎受到皮质神经元原始反应边界的限制。
