[Heat loss and tissue metabolism in albino mice after acute hypothermia].

Constant heat loss studied by direct calorimetry is decreased during acute hypothermia induced by 30-40 min exposure at -6 degrees C, and body temperature falls by 7-9 degrees. Heat production is restored within 35-40 min. Cooling of the animals at -11.8 degrees leads to a fall in body temperature by more than 10 degrees, and restitution sets in about 25 min. Brain tissue respiration (incubation at 23 and 33 degrees) is increased at the 5th and 45th min after hypothermia with no changes in Q10-respiration. The metabolism of heart and liver tissues and skeletal muscles is increased at 5th, 40th and 105th min of restitution; Q10 of skeletal muscle respiration is decreased after 105-min restitution. Temperature compensation for metabolism as the mechanism of tissue homeostasis obvious during arousal in hibernating animals, is absent in non-hibernating heterothermal animals.