Thompson F J, Barnes C D, Wald J R
J Auton Nerv Syst. 1982 Sep;6(2):113-26. doi: 10.1016/0165-1838(82)90045-5.
This study reports findings of spinal reflex connections of afferent fibers electrically excited in the wall of the femoral vein. Condition-test experiments, and EMG recordings revealed that the femoral venous afferents have facilitatory connections to flexor and extensor motoneurons of both the proximal and the distal hindlimb muscles. Femoral venous afferent stimulation which produced facilitation, also produced inhibition of the test reflexes following the facilitation. Because the inhibition was enhanced by diazepam injection and because the inhibitory time-course correlated closely to the time-courses of both dorsal root potentials and individual tests of primary afferent depolarization, the inhibition was suggested to be produced by presynaptic inhibition. The potentially significant role of the venous afferent connections in a reflex-elicited skeletal muscle pump or in an increase in intramuscular venous counterpressure is discussed.
本研究报告了在股静脉壁上电刺激传入纤维的脊髓反射连接的研究结果。条件-测试实验和肌电图记录显示，股静脉传入纤维与近端和远端后肢肌肉的屈肌和伸肌运动神经元具有易化性连接。产生易化作用的股静脉传入纤维刺激，在易化作用之后也会对测试反射产生抑制作用。由于注射地西泮可增强这种抑制作用，且抑制的时间进程与背根电位和初级传入去极化的个体测试的时间进程密切相关，因此提示这种抑制是由突触前抑制产生的。文中讨论了静脉传入连接在反射诱发的骨骼肌泵或肌肉内静脉反压增加中可能具有的重要作用。
