Monnier J C, Wattecamps J, Lanciaux B, Dognin C, Farine M O
J Gynecol Obstet Biol Reprod (Paris). 1982;11(5):599-605.
The condition is extremely rare, since acardia is only found in 1% of monozygotic twin pregnancies. A case was discovered and observed using ultrasound and was then studied anatomically and pathologically. The histopathology and the physiopathology of the malformation is described. The aetiology that has been most usually accepted is that there is an anastomosis between the two umbilical cords of the two "twins" and that this leads to an inversion of the direction of the circulation in the affected fetus. The failure of the myocardium to develop would follow this vascular abnormality because of failure of the allantoid vessels to fuse. The interest in this kind of observation lies in the possibility of making the diagnosis very early in pregnancy using ultrasound, and of following the evolution and the regression of the acardiac fetus throughout the pregnancy, and with the possibility of comparing the views obtained by ultrasound with the anatomo-pathological features that can be diagnosed after birth.
这种情况极为罕见，因为无心畸形仅在1%的单卵双胎妊娠中出现。发现了一例病例，并通过超声进行观察，随后进行了解剖学和病理学研究。描述了该畸形的组织病理学和病理生理学。最常被接受的病因是两个“双胞胎”的两条脐带之间存在吻合，这导致受影响胎儿的血液循环方向反转。由于尿囊血管未能融合，心肌发育失败将继发于这种血管异常。这类观察的意义在于有可能在妊娠早期通过超声做出诊断，并在整个孕期跟踪无心胎儿的演变和消退，还能够将超声检查结果与出生后可诊断的解剖病理学特征进行比较。
