Berkovitz G D, Rock J A, Urban M D, Migeon C J
Johns Hopkins Med J. 1982 Dec;151(6):290-7.
Eleven cases of true hermaphroditism (eight previously reported) studied at The Johns Hopkins Hospital are presented. The two most recently observed patients had what is to be considered an appropriate endocrine evaluation. This includes karyotyping, and measurement of 24-hour urinary 17-ketosteroids, gonadotropins, plasma testosterone, dihydrotestosterone, and all their precursors before and following a human chorionic gonadotropin stimulation test, and a sexual skin biopsy for androgen receptor binding and 5 alpha-reductase activity. The differential diagnosis of true hermaphroditism is discussed and an approach to gender assignment is presented.
本文介绍了在约翰霍普金斯医院研究的11例真两性畸形病例（其中8例此前已有报道）。最近观察的2例患者接受了被认为是适当的内分泌评估。这包括染色体核型分析、24小时尿17-酮类固醇、促性腺激素、血浆睾酮、双氢睾酮及其在人绒毛膜促性腺激素刺激试验前后所有前体的测定，以及用于雄激素受体结合和5α-还原酶活性的性皮肤活检。文中讨论了真两性畸形的鉴别诊断，并提出了性别分配的方法。
