Bowman J P
J Speech Hear Res. 1982 Sep;25(3):348-56.
Afferents present in the distal hypoglossal nerve of the rhesus monkey include fibers derived from lingual muscle spindles. Using the evoked-potential technique in rhesus monkeys, the objective of this study was to determine whether the medial lemniscus (ML) represents the rostral projection path for hypoglossal afferent information. Responses evoked by low-intensity stimulation of the XIIth nerve were recorded with bipolar macroelectrodes at medullary, pontine, and midbrain levels in pentobarbital or urethane anesthestized animals. Results indicate that fibers related to XIIth nerve afferents ascend in association with the contralateral ML. This projection mediates the contralateral thalamic and cerebrocortical potentials shown in previous studies to be evoked by XIIth nerve stimuli. The role this projection may play in tongue sensorimotor function is discussed. Results also demonstrate the presence of contralateral responses in the medial portion of the pontine reticulotegmental nucleus. These medially located potentials were isolated from responses evoked from the ML by intervening unresponsive electrode tracks suggesting that a component of the lemniscal projection may terminate in the "face zone" of this precerebellar relay.
恒河猴舌下神经远端存在的传入神经包括来自舌肌梭的纤维。本研究利用恒河猴的诱发电位技术，目的是确定内侧丘系（ML）是否代表舌下神经传入信息的 Rostral 投射路径。在戊巴比妥或氨基甲酸乙酯麻醉的动物中，用双极宏观电极在延髓、脑桥和中脑水平记录第十二神经低强度刺激诱发的反应。结果表明，与第十二神经传入相关的纤维与对侧 ML 一起上升。该投射介导了先前研究中显示由第十二神经刺激诱发的对侧丘脑和大脑皮质电位。讨论了该投射在舌感觉运动功能中可能发挥的作用。结果还证明在脑桥网状被盖核内侧部分存在对侧反应。这些位于内侧的电位通过插入无反应的电极轨迹与 ML 诱发的反应分离，表明丘系投射的一个成分可能终止于这个小脑前中继的“面部区”。
