Chilla R, Evers K
Laryngol Rhinol Otol (Stuttg). 1982 Nov;61(11):618-21.
Following skin damage resulting from radiotherapy, pancancerous conditions, carcinomas and basal cell carcinomas not rarely pose therapeutic problems. We encountered those problems severally after radiotherapy of the middle face, for instance for lupus vulgaris or basal cell carcinoma. Senile skin changed over the years by climatological influences may create similar problems. Disorders of blood supply and lack of "tissue material" as consequences of radiation-induced skin atrophy are the reasons for the failure of many attempts of plastic surgery aimed at tumor removal and defect repair. Besides that, the conditions for such operative procedures are progressively deteriorating with the number of tumor recurrences. In these instances cryotherapy offers an excellent therapeutic alternative by virtue of the favorable healing tendency of the cryonecrosis including the final, inconspicuous scar formation.
放疗导致皮肤损伤后，多种癌症、癌和基底细胞癌常常会带来治疗难题。例如，在中面部放疗后，如寻常狼疮或基底细胞癌，我们就多次遇到这些问题。多年来受气候影响而发生变化的老年皮肤也可能引发类似问题。放疗引起的皮肤萎缩导致的血液供应紊乱和“组织材料”缺乏，是许多旨在切除肿瘤和修复缺损的整形手术失败的原因。除此之外，随着肿瘤复发次数的增加，此类手术的条件也在逐渐恶化。在这些情况下，冷冻疗法凭借冷冻坏死良好的愈合趋势，包括最终形成不明显的瘢痕，提供了一种极佳的治疗选择。
