Cascio C S, Kellar K J
Neuropharmacology. 1982 Nov;21(11):1219-21. doi: 10.1016/0028-3908(82)90185-x.
The affinities of four tetrahydro-beta-carbolines at [3H]tryptamine, [3H]5-HT (5-HT1), and [3H]spiperone (5-HT2) binding sites in rat cerebral cortex were investigated. The unsubstituted tetrahydro-beta-carboline was the most potent of the four compounds at all three binding sites, but was 200-400 times more potent at the tryptamine site than at either of the serotonin sites.
