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[生命最初几个月婴儿中枢神经系统永久性器质性病变发生和形成过程中危险因素的意义]

[Significance of risk factors in the development and formation of permanent organic lesions of the central nervous system in infants during the 1st few months of life].

作者信息

Zemlianskaia Z K, Burkova A S, Kobrinskiĭ B A, Iakunin Iu A, Iampol'skaia E I

出版信息

Zh Nevropatol Psikhiatr Im S S Korsakova. 1982;82(10):46-51.

PMID:7180281
Abstract

Data obtained from examining 350 full-term newborns and infants of up to 4 months of age with pre- and perinatal encephalopathies were processed mathematically. As a result, factors pointing to a high risk of development of functional cerebral disorders and formation of early organic syndromes in infants of the first 4 months of life were specified. As the basis for this a chart devised with the aid of the expert evaluation method was taken. The chart included 42 signs with 98 gradations (occupational unhealthy factors, family and obstetrical history, course of pregnancy and childbirth, clinical characteristics of the neurological manifestations in the acute and early restorative periods). A high prognostic value of combining some factors, symptom complexes, clinical and laboratory findings is demonstrated: such combinations are very important for early diagnosis of organic cerebral pathologies. The use of those combinations has made it possible to identify (with the aid of a computer) 95.6% of infants with a threat of early development of organic changes in the central nervous system.

摘要

对350名患有围产期和产前脑病的足月儿及4个月以下婴儿进行检查所获得的数据进行了数学处理。结果,明确了指向4个月以下婴儿发生功能性脑障碍及形成早期器质性综合征高风险的因素。以此为基础采用专家评估法设计了一张图表。该图表包括42个体征及98个分级(职业性有害因素、家庭和产科病史、妊娠和分娩过程、急性期及早期恢复期神经表现的临床特征)。证明了某些因素、症状组合、临床和实验室检查结果相结合具有很高的预后价值:这种组合对早期诊断器质性脑病变非常重要。使用这些组合能够(借助计算机)识别出95.6%有中枢神经系统早期器质性改变风险的婴儿。

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