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心理生理发育异常青少年的临床生化相关性

[Clinico-biochemical correlates in adolescents with abnormal rates of psychophysical development].

作者信息

Zhitlovskiĭ V E, Tananova G V, Bushuev S L

出版信息

Zh Nevropatol Psikhiatr Im S S Korsakova. 1982;82(11):95-100.

PMID:7180312
Abstract

The authors examined 106 adolescents with behaviour anomalies treated at Daytime Psychotherapeutic Ward of Moscow Children's Psychiatric Hospital No. 6. In 96 of them, borderline neuropsychic disturbances and in 10 schizophrenia were diagnosed. A correlation between the clinical signs of the personality dysharmonic formation and the lipid composition of the blood plasma was revealed. It is shown that all the adolescents with the anomalous behaviour have hyperlipidemia with prevalence of the processes of lipolysis in patients with signs of acceleration, and of lipid synthesis in patients with retardation. In the schizophrenic patients a deficit of phospholipids and alpha-lipoproteids was observed. All the patients showed hypercholesterolemia, which, however, had certain peculiarities in each group. The lipid metabolism disorders revealed may be a cause of an intensification of psychomotor activity that may lead in a certain socio-psychological environment to behaviour anomalies of delinquent character.

摘要

作者对在莫斯科第6儿童医院日间心理治疗病房接受治疗的106名有行为异常的青少年进行了检查。其中96人被诊断为边缘性神经精神障碍,10人被诊断为精神分裂症。研究发现人格不协调形成的临床症状与血浆脂质成分之间存在相关性。结果表明,所有行为异常的青少年都有高脂血症,在有加速迹象的患者中脂解过程占优势,而在发育迟缓的患者中脂质合成占优势。在精神分裂症患者中观察到磷脂和α-脂蛋白缺乏。所有患者均表现为高胆固醇血症,然而,每组都有一定的特点。所揭示的脂质代谢紊乱可能是精神运动活动增强的一个原因,在一定的社会心理环境中,这可能导致具有犯罪性质的行为异常。

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