Szatmáry L, Medvedowsky J L, Barnay C, Medvedowsky A, Pisapia A, Delaage L, Veress G, Pinot J J, Jouve A, Torresani J
Acta Med Acad Sci Hung. 1982;39(1-2):47-61.
The sympathetic and parasympathetic neurological cardiac effects were blocked with atropine and propranolol. The intrinsic heart rate (IHR) was determined and rapid atrial pacing (RAP) was carried out before and after administration of the drugs. The primary and secondary postpacing parameters were examined in both circumstances. Normal (n = 31) and pathological (n = 20) cases were differentiated on the basis of the IHR. In the secondary phase (PPC 2-10) after autonomic blockade returned to the basic frequency was of exponential character in the great majority of normal IHR cases. Anomalies may appear in both the primary and secondary phases. They are of different types: one of them concerns the recovery time; another electrophysiological anomaly occurs when there is no return to the predrive normal cycle length after pharmacological neurotomy. In the secondary phase there may appear sinoauricular blocks. They may depend on or appear independently of the effect of the vegetative nervous system. The new test allows a physiopathological classification of normal and pathological sinus node function.
使用阿托品和普萘洛尔阻断交感神经和副交感神经对心脏的作用。测定固有心率（IHR），并在给药前后进行快速心房起搏（RAP）。在两种情况下均检查起搏前后的主要和次要参数。根据IHR区分正常（n = 31）和病理（n = 20）病例。在自主神经阻断恢复到基本频率后的第二阶段（PPC 2-10），绝大多数正常IHR病例呈指数特征。在第一阶段和第二阶段都可能出现异常。它们有不同类型：一种涉及恢复时间；另一种电生理异常发生在药理学神经切断术后未恢复到驱动前正常周期长度时。在第二阶段可能出现窦房阻滞。它们可能取决于或独立于自主神经系统的作用而出现。这项新测试允许对正常和病理性窦房结功能进行生理病理学分类。
