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相似文献

1
Successful treatment of gallstones with bile acids in obese adolescents.胆汁酸成功治疗肥胖青少年胆结石
Arch Dis Child. 1982 Dec;57(12):956-8. doi: 10.1136/adc.57.12.956.
2
Dissolving gallstones.溶解胆结石
Med J Aust. 1980 May 17;1(10):456-7. doi: 10.5694/j.1326-5377.1980.tb135035.x.
3
The medical treatment of gallstones.
Annu Rev Med. 1980;31:59-77. doi: 10.1146/annurev.me.31.020180.000423.
4
Medical therapy for gallstones. 1. Rationale and indications.胆结石的医学治疗。1. 基本原理和适应症。
Postgrad Med. 1982 May;71(5):163-72. doi: 10.1080/00325481.1982.11716072.
5
Comparison of effects of chenodeoxycholic and ursodeoxycholic acid and their combination on biliary lipids in obese patients with gallstones.
Scand J Gastroenterol. 1991 Mar;26(3):257-62. doi: 10.3109/00365529109025039.
6
Changes in serum bile acids during treatment with chenodiol or ursodiol for dissolution of cholesterol gallstones.用鹅去氧胆酸或熊去氧胆酸治疗胆固醇结石溶解过程中血清胆汁酸的变化。
Mt Sinai J Med. 1983 May-Jun;50(3):240-4.
7
[New therapeutic methods--technics, application, efficacy and problems. Litholysis. a) Theory of litholysis and development of litholytic agents].[新的治疗方法——技术、应用、疗效及问题。溶石疗法。a) 溶石理论及溶石剂的发展]
Nihon Rinsho. 1987 Jul;45(7):1539-46.
8
Bile acids in health and disease.健康与疾病中的胆汁酸。
Lancet. 1987 Nov 14;2(8568):1140-2. doi: 10.1016/s0140-6736(87)91560-1.
9
Effect of litholytic bile acids on cholesterol absorption in gallstone patients.溶石胆汁酸对胆结石患者胆固醇吸收的影响。
Gastroenterology. 1983 Feb;84(2):265-71.
10
[Medical treatment of gallstones (author's transl)].
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本文引用的文献

1
Cholesterol cholelithiasis in adolescent females: its connection with obestiy, parity, and oral contraceptive use--a retrospective study of 31 cases.青春期女性胆固醇性胆结石:其与肥胖、生育及口服避孕药使用的关系——31例回顾性研究
Arch Surg. 1980 Jan;115(1):62-4. doi: 10.1001/archsurg.1980.01380010054010.
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Cholecystectomy and carcinoma of the colon.胆囊切除术与结肠癌
Lancet. 1981 Aug 22;2(8243):379-81. doi: 10.1016/s0140-6736(81)90829-1.
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Cholelithiasis in childhood.儿童胆结石
Am J Surg. 1974 Jun;127(6):689-92. doi: 10.1016/0002-9610(74)90348-1.
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Metabolic epidemiology of colon cancer. Fecal bile acids and neutral sterols in colon cancer patients and patients with adenomatous polyps.结肠癌的代谢流行病学。结肠癌患者和腺瘤性息肉患者粪便中的胆汁酸和中性固醇。
Cancer. 1977 Jun;39(6):2533-9. doi: 10.1002/1097-0142(197706)39:6<2533::aid-cncr2820390634>3.0.co;2-x.
5
Critical tables for calculating the cholesterol saturation of native bile.用于计算天然胆汁胆固醇饱和度的关键表格。
J Lipid Res. 1978 Nov;19(8):945-55.
6
Resistance to chenodeoxycholic acid (CDCA) treatment in obese patients with gall stones.肥胖胆结石患者对鹅去氧胆酸(CDCA)治疗的耐药性。
Br Med J. 1978 Jun 10;1(6126):1509-12. doi: 10.1136/bmj.1.6126.1509.
7
Risk factors for the development of cholelithiasis in man (second of two parts).人类胆石症形成的危险因素(两部分中的第二部分)
N Engl J Med. 1978 Nov 30;299(22):1221-7. doi: 10.1056/NEJM197811302992205.
8
Ursodeoxycholic acid versus chenodeoxycholic acid. Comparison of their effects on bile acid and bile lipid composition in patients with cholesterol gallstones.熊去氧胆酸与鹅去氧胆酸。胆固醇结石患者中二者对胆汁酸和胆汁脂质成分影响的比较。
Gastroenterology. 1978 Dec;75(6):1016-20.

胆汁酸成功治疗肥胖青少年胆结石

Successful treatment of gallstones with bile acids in obese adolescents.

作者信息

Podda M, Zuin M, Dioguardi M L, Festorazzi S

出版信息

Arch Dis Child. 1982 Dec;57(12):956-8. doi: 10.1136/adc.57.12.956.

DOI:10.1136/adc.57.12.956
PMID:7181529
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1628058/
Abstract

Six obese adolescents (4 girls, 2 boys) with radiolucent gallstones were treated with bile acids (chenodeoxycholic or ursodeoxycholic acid). Each had lithogenic bile and no predisposing factors for pigment stone formation. Within 12 months, the bile became unsaturated with cholesterol and the gallstones had disappeared in 4 cases and were decreased in size in two.

摘要

六名患有透光性胆结石的肥胖青少年(4名女孩,2名男孩)接受了胆汁酸(鹅去氧胆酸或熊去氧胆酸)治疗。他们的胆汁均有形成结石的倾向,且无色素结石形成的诱发因素。在12个月内,胆汁中的胆固醇变为不饱和状态,4例患者的胆结石消失,2例患者的胆结石体积减小。