胆汁酸成功治疗肥胖青少年胆结石
Successful treatment of gallstones with bile acids in obese adolescents.
作者信息
Podda M, Zuin M, Dioguardi M L, Festorazzi S
出版信息
Arch Dis Child. 1982 Dec;57(12):956-8. doi: 10.1136/adc.57.12.956.
Abstract
Six obese adolescents (4 girls, 2 boys) with radiolucent gallstones were treated with bile acids (chenodeoxycholic or ursodeoxycholic acid). Each had lithogenic bile and no predisposing factors for pigment stone formation. Within 12 months, the bile became unsaturated with cholesterol and the gallstones had disappeared in 4 cases and were decreased in size in two.
摘要
六名患有透光性胆结石的肥胖青少年（4名女孩，2名男孩）接受了胆汁酸（鹅去氧胆酸或熊去氧胆酸）治疗。他们的胆汁均有形成结石的倾向，且无色素结石形成的诱发因素。在12个月内，胆汁中的胆固醇变为不饱和状态，4例患者的胆结石消失，2例患者的胆结石体积减小。
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