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[新生儿促甲状腺激素放射免疫测定中不同质量滤纸的方法学研究]

[Methodological study of different qualities of filter paper in the radioimmunological determination of thyrotropin in newborn infants].

作者信息

Höpfner B

出版信息

J Clin Chem Clin Biochem. 1982 Dec;20(12):915-20.

PMID:7182429
Abstract

In the screening of newborns for congenital hypothyroidism, filter paper cards act as sample carriers for capillary blood specimens, and for reference quantities of the measured hormones. Therefore, the quality of the filter paper is especially important and must be taken into account. Different types of filter paper and different guide marks on the paper surface for spotting blood specimens were investigated. The hormone distribution within the dried blood spot and the time necessary to extract the hormones were examined in relation to the sensitivity and yield of the test kit.

摘要

在新生儿先天性甲状腺功能减退症筛查中,滤纸卡片用作毛细血管血标本以及所测激素参考量的样本载体。因此,滤纸的质量尤为重要,必须予以考虑。研究了不同类型的滤纸以及纸表面用于血标本点样的不同引导标记。针对检测试剂盒的灵敏度和产量,考察了干血斑内激素的分布情况以及提取激素所需的时间。

相似文献

1
[Methodological study of different qualities of filter paper in the radioimmunological determination of thyrotropin in newborn infants].[新生儿促甲状腺激素放射免疫测定中不同质量滤纸的方法学研究]
J Clin Chem Clin Biochem. 1982 Dec;20(12):915-20.
2
Adaptation of TSH filter paper method for regionalized screening for congenital hypothyroidism.
J Lab Clin Med. 1977 Jul;90(1):11-7.
3
The investigation of factors influencing the measurement of thyroid stimulating hormone in dried blood spots on filter paper.滤纸干血斑中影响促甲状腺激素测量的因素研究
Southeast Asian J Trop Med Public Health. 2003;34 Suppl 3:147-9.
4
[Screening for congenital hypothyroidism with an immunoradiometric assay (IRMA) for thyroid stimulating hormone].
Monatsschr Kinderheilkd. 1986 Jan;134(1):25-7.
5
[Development of a radioimmunoassay for thyrotropin (TSH) in dried blood spots together with a comparison of 7 commercial kits (author's transl)].干血斑中促甲状腺激素(TSH)放射免疫测定法的开发及7种市售试剂盒的比较(作者译)
J Clin Chem Clin Biochem. 1980 Nov;18(11):807-16.
6
Screening for congenital hypothyroidism (CH) among Filipino newborn infants. Philippine Newborn Screening Study Group.菲律宾新生儿先天性甲状腺功能减退症(CH)筛查。菲律宾新生儿筛查研究小组。
Southeast Asian J Trop Med Public Health. 1999;30 Suppl 2:20-2.
7
Early detection of neonatal hypothyroidism by serial TSH determination in dried blood. Six months experience with a reliable, efficient and inexpensive method.
Helv Paediatr Acta. 1977 Nov;32(4-5):289-97.
8
TSH assay using dried blood samples: a screening method for congenital hypothyroidism.使用干血样进行促甲状腺激素检测:一种先天性甲状腺功能减退症的筛查方法。
Bangladesh Med Res Counc Bull. 1999 Aug;25(2):27-34.
9
Problems in screening for congenital hypothyroidism using thyroxine assays from small dried blood discs.
J Nucl Med. 1981 Sep;22(9):818-23.
10
Blood-spot thyrotropin radioimmunoassay in a screening program for congenital hypothyroidism.先天性甲状腺功能减退症筛查项目中的血斑促甲状腺素放射免疫测定法。
Clin Chem. 1979 Jun;25(6):933-8.