Papo I, Caruselli G, Luongo A
J Neurosurg Sci. 1982 Jul-Sep;26(3):193-8.
Long-term ICP monitoring was carried out in 53 children and adolescents with severe head injuries. 36 of them exhibited bilateral decerebrate posturing and 13 bilateral pupil unresponsiveness. The highest ICP levels never exceeded 10 mmHg in 3 patients, ranged between 11 and 20 mmHg in 12 and between 21 and 50 in 16. Fifteen patients showed sustained intracranial hypertension over 50 mmHg. Six patients died from fulminating intracranial hypertension and 21 died later (average survival 10.1 days). Five patients remained severely disabled and 21 satisfactorily recovered. Seven patients with the highest degrees of intracranial hypertension survived, in all of them ICP reached its peak more than 72 hours after injury. Early hypertension exceeding 50 mmHg always proved fatal. Four patients with mild hypertension but with very high elastance on P/V tests died. Although children and adolescents may withstand higher degrees of intracranial hypertension than adults, outcome remains poor despite active therapy in ICU patients with deep stabilised coma.
对53名重度颅脑损伤的儿童和青少年进行了长期颅内压(ICP)监测。其中36人出现双侧去大脑强直姿势,13人双侧瞳孔无反应。3例患者的最高ICP水平从未超过10 mmHg,12例在11至20 mmHg之间,16例在21至50 mmHg之间。15例患者出现持续颅内高压超过50 mmHg。6例患者死于暴发性颅内高压,21例随后死亡(平均存活10.1天)。5例患者仍严重残疾,21例恢复良好。7例颅内高压程度最高的患者存活下来,他们的ICP均在受伤72小时后达到峰值。早期高血压超过50 mmHg总是致命的。4例轻度高血压但P/V试验弹性非常高的患者死亡。尽管儿童和青少年可能比成年人承受更高程度的颅内高压,但对于ICU中深度稳定昏迷的患者,尽管进行了积极治疗,预后仍然很差。