Hargadine J R, Snyder E
Bull Los Angeles Neurol Soc. 1982;47:62-75.
Intraoperative monitoring of the brain's electrical function with evoked potentials (EPs) may prove as valuable as cardiac monitoring in detecting abnormalities before permanent damage occurs. To date, evoked potential monitoring has only been employed in select neurological cases, where the significance of electrical changes can be related to postoperative deficits. If EP intraoperative techniques are to be useful in preventing these postoperative deficits, they must be able to predict impending brain dysfunction during surgery. There is strong clinical and experimental data relating EP changes to critical blood flow, brain retraction, and CNS manipulation. However, little is known of the normal fluctuations in electrical activity during routine non-neurological surgery. The data we have collected in control patients (non-neurological) will be a guide to the interpretation of neurological cases (carotid endarterectomy, aneurysm, and cervical spine and cord lesions). We have concentrated on monitoring somatosensory and auditory short-latency EPs since they appear to be the most stable, reproducible and the most applicable to patient monitoring during neurosurgical, vascular and orthopedic procedures.
术中通过诱发电位(EP)监测大脑的电功能,在检测永久性损伤发生前的异常情况方面,可能与心脏监测一样有价值。迄今为止,诱发电位监测仅在特定的神经病例中使用,其中电变化的意义可与术后缺陷相关联。如果术中EP技术要用于预防这些术后缺陷,它们必须能够预测手术期间即将出现的脑功能障碍。有强有力的临床和实验数据将EP变化与临界血流、脑牵拉和中枢神经系统操作联系起来。然而,对于常规非神经外科手术期间电活动的正常波动知之甚少。我们在对照患者(非神经外科)中收集的数据将为解释神经病例(颈动脉内膜切除术、动脉瘤以及颈椎和脊髓病变)提供指导。我们专注于监测体感和听觉短潜伏期EP,因为它们似乎是最稳定、可重复且最适用于神经外科、血管和骨科手术期间患者监测的。