Champakam N S, D'Souza V, Kamat J R, Parashar S K
Int Surg. 1982 Oct-Dec;67(4 Suppl):425-6.
Fifty breast lumps seen and operated on at the Goa Medical College Hospital over a one year period form the material for this study. The cases were at first diagnosed clinically. At operation a naked eye assessment of the malignancy of the excised breast lump was made. Slide imprints for cytodiagnosis were made and finally the excised mass sent for paraffin section study. A rapid diagnosis of these 50 surgically removed breast lumps was thus made by naked eye examination and imprint cytodiagnosis and the results were compared with routine paraffin section diagnosis which is considered the final diagnosis. An analysis of the results show that naked eye examination of the excised breast lump distinguished between malignant and non-malignant lumps correctly in 96% of cases, rapid imprint cytodiagnosis was correct in 98% of cases, clinical diagnosis in 96% of cases and aspiration cytodiagnosis in all cases. Naked eye examination of the mass prior to imprinting would help to decide the correct pressure to be used to avoid false results.
本研究的资料来源于果阿医学院医院在一年时间内收治并接受手术的50例乳腺肿块。这些病例首先经过临床诊断。手术时,对切除的乳腺肿块进行肉眼恶性程度评估。制作用于细胞诊断的涂片印记,最后将切除的肿块送去做石蜡切片研究。通过肉眼检查和印记细胞诊断对这50例手术切除的乳腺肿块做出快速诊断,并将结果与被视为最终诊断的常规石蜡切片诊断进行比较。结果分析表明,对切除的乳腺肿块进行肉眼检查在96%的病例中能正确区分恶性和非恶性肿块,快速印记细胞诊断在98%的病例中正确,临床诊断在96%的病例中正确,而穿刺细胞诊断在所有病例中均正确。在制作印记之前对肿块进行肉眼检查有助于确定正确的施压力度以避免出现错误结果。