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膀胱平滑肌电活动:对阿托品和氨甲酰甲胆碱的反应。

Urinary bladder smooth-muscle electrical activity: response to atropine and bethanechol.

作者信息

Kaplan P E, Nanninga J B, Lal S

出版信息

Arch Phys Med Rehabil. 1978 Oct;59(10):454-8.

PMID:718409
Abstract

Fourteen patients with spinal cord injuries and lower motor neuron type neurogenic bladders and 12 patients with upper motor neuron type neurogenic bladders and spinal cord injuries, were evaluated before and after bethanechol or atropine, respectively. They were compared with 5 patients with benign prostatic hypertrophy or bladder tumors but without neurologic disease. Both drugs were found to modify partially smooth-muscle response. The implications of these results are consistent with the production of electrical activity by the smooth-muscle cells of the bladder wall.

摘要

分别对14例患有脊髓损伤及下运动神经元型神经源性膀胱的患者以及12例患有上运动神经元型神经源性膀胱及脊髓损伤的患者,在使用氨甲酰甲胆碱或阿托品前后进行了评估。将他们与5例患有良性前列腺增生或膀胱肿瘤但无神经疾病的患者进行了比较。发现两种药物均能部分改变平滑肌反应。这些结果表明膀胱壁平滑肌细胞会产生电活动。

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Arch Phys Med Rehabil. 1978 Oct;59(10):454-8.
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