Voshchinina O N
Arkh Anat Gistol Embriol. 1978 Sep;75(9):56-9.
Diurnal density of the capillary network and the activity of butyrilcholinesterase and alkaline phosphatase in the capillary wall of the rat medulla oblongata and mesencephalon have been studied. Maximum activity of butyrilcholinesterase has been stated to be in the day time (12--15 a. m.) and minimum--at night (24 p. m.). In the activity of alkaline phosphatase two peaks are noted: in the morning (9--12 a. m.) and in the evening (21 p. m.). Decrease in the activity of the two substances is observed at 24 p. m. Since these two enzymes participate, to a certain degree, in metabolic and barrier function of brain capillaries, a conclusion is made on diurnal fluctuations in the level of the brain capillary blood circulation. It is recommended to take into account the circadian rhythms of the capillary blood circulation while investigating brain capillary circulation in practice.
对大鼠延髓和中脑毛细血管网络的日密度以及毛细血管壁中丁酰胆碱酯酶和碱性磷酸酶的活性进行了研究。已表明丁酰胆碱酯酶的最大活性出现在白天（上午12点至下午3点），而最低活性出现在夜间（晚上12点）。碱性磷酸酶的活性有两个峰值：分别在早晨（上午9点至12点）和晚上（晚上9点）。在晚上12点观察到这两种物质的活性降低。由于这两种酶在一定程度上参与脑毛细血管的代谢和屏障功能，因此得出关于脑毛细血管血液循环水平存在日波动的结论。建议在实际研究脑毛细血管循环时考虑毛细血管血液循环的昼夜节律。
