Tajima M
Gan To Kagaku Ryoho. 1982 Oct;9(10):1688-94.
Diagnostic cytology may be of use for some information in the field of cancer treatment. From the view point of morphological characteristics of cancer cells which are obtained before treatment, we can presume the prognostic courses in certain level. For example, presumption of prognosis on 420 cases with uterine cervix carcinomas according to their cytological findings before therapy (Cobalt irradiation), showed 77% in its accuracy rate. Particularly 144 cases, which were classified to FIGO Stage III were tested by cytological method, accuracy rate of prognostic presumption showed 76%. On the other hand, presumption of prognosis on same cases by means of histological method showed 68% in its accuracy rate. On the base of morphological change of cancer cells, therapeutic effects can be checked during the treatment. Reoccurrence may be recognized in early stage when any subjective or clinical symptoms manifest. Alteration of cell components, except cancer cell, shows sometimes a relation with clinical course. In pleuroperitoneal effusions, numerical alterations of macrophage and lymphocyte are valuable factors which relate to clinical course and outcome of cancer patients.
诊断细胞学在癌症治疗领域可能会提供一些有用信息。从治疗前获取的癌细胞形态学特征来看，我们可以在一定程度上推测预后情况。例如，根据420例子宫颈癌治疗前（钴放疗）的细胞学检查结果进行预后推测，准确率为77%。特别是对144例FIGO分期为III期的病例采用细胞学方法进行检测，预后推测准确率为76%。另一方面，采用组织学方法对相同病例进行预后推测，准确率为68%。基于癌细胞的形态变化，可以在治疗过程中检查治疗效果。当出现任何主观或临床症状时，可在早期识别复发情况。除癌细胞外，细胞成分的改变有时与临床病程有关。在胸腔积液和腹腔积液中，巨噬细胞和淋巴细胞的数量变化是与癌症患者临床病程和预后相关的重要因素。
