Aoki K, Sasaki R, Mizuno S
Gan To Kagaku Ryoho. 1982 May;9(5):766-73.
In human cancers, the contribution of genetic determinants is often difficult to distinguish from environmental influences. However, some cancers are inherited in Mendelian pattern, and some have closely associated with the diseases with hereditary factors. This paper reviewed characteristics of hereditary cancers, the diseases with high incidence of cancers and familial aggregation of cancers, and discussed the role of host factors in the etiology of cancer clinico-epidemiologically.
在人类癌症中，遗传决定因素的作用往往难以与环境影响区分开来。然而，一些癌症以孟德尔方式遗传，还有一些与具有遗传因素的疾病密切相关。本文综述了遗传性癌症、癌症高发疾病以及癌症家族聚集性的特征，并从临床流行病学角度探讨了宿主因素在癌症病因学中的作用。
