氯喹与正常血清和夸休可尔症血清的结合
The binding of chloroquine to normal and Kwashiorkor serum.
作者信息
Buchanan N, Van der Walt L A
出版信息
Am J Trop Med Hyg. 1977 Sep;26(5 Pt 1):1025-7. doi: 10.4269/ajtmh.1977.26.1025.
PMID:71861
Abstract
The binding of chloroquine to kwashiorkor and normal serum was investigated. The results show that more drug is bound in kwashiorkor serum, and that this occurs predominantly at the gamma globulin fraction. Therapeutically, in malnutrition there is no significant abnormality of protein binding with respect to chloroquine.
摘要
研究了氯喹与夸休可尔症血清和正常血清的结合情况。结果表明，氯喹在夸休可尔症血清中的结合量更多，且这种结合主要发生在γ球蛋白部分。在治疗方面，在营养不良的情况下，氯喹的蛋白结合没有明显异常。
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