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[与萎缩性慢性胃炎和胃溃疡相关的癌前病变]

[Precancerous lesions associated with atrophic chronic gastritis and gastric peptic ulcer].

作者信息

Nogueira A M, Barbosa C S, Miranda D

出版信息

Arq Gastroenterol. 1982 Oct-Dec;19(4):169-74.

PMID:7186401
Abstract

Among the gastric lesions related to an increased risk for gastric cancer (precancerous conditions) two have deserved special attention, i.e., atrophic gastritis and peptic ulcer. In this paper the authors study the incidence of glandular dysplasia in atrophic gastritis and gastric peptic ulcer. In 148 cases of atrophic gastritis dysplastic lesions were diagnosed in 92 (62,0%): 63 cases (68,4%) with mild dysplasia, 25 cases (27,0%) with moderate dysplasia and 4 cases (4,3%) with severe dysplasia. In 329 gastric peptic ulcers examined there were 51 (15,5%) with dysplastic lesions: in 34 cases (66,6%) there was mild dysplasia, 12 cases (23,5%) moderate dysplasia and (9,8%) severe dysplasia. A prospective study with histological multiple sections from the stomach would be helpful for better understanding of these precancerous lesions.

摘要

在与胃癌风险增加相关的胃部病变(癌前状况)中,有两种受到了特别关注,即萎缩性胃炎和消化性溃疡。在本文中,作者研究了萎缩性胃炎和胃消化性溃疡中腺体发育异常的发生率。在148例萎缩性胃炎病例中,92例(62.0%)诊断出发育异常病变:63例(68.4%)为轻度发育异常,25例(27.0%)为中度发育异常,4例(4.3%)为重度发育异常。在检查的329例胃消化性溃疡中,有51例(15.5%)存在发育异常病变:34例(66.6%)为轻度发育异常,12例(23.5%)为中度发育异常,5例(9.8%)为重度发育异常。对胃进行组织学多切片的前瞻性研究将有助于更好地理解这些癌前病变。

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