Effects of ethanol and various dietary fats on the levels of thiamine, riboflavin, niacin and folacin in the liver.

The experiment was designed to study the effect of ethanol and different fats on content in the liver of some vitamins of B group. The Wistar rats, during 6 months and 12 months were kept on fully sufficient isocaloric diets containing 30% kcal from sunflower oil, rapeseed oil, liquid fish fat, hardened fish fat and mixed fat, that is lard, butter and sunflower oil. Some animals obtained daily in drinking water increasing doses of ethanol from 2.5% to 25%. It was found that the amount of thiamin and niacin was similar in the livers of rats fed different fats in relation of rats fed mixed fats, while the level of folacin was higher in rats on sunflower oil. The chronic ethanol administration decreased the level of studied vitamins in the livers in different degree dependently on the kind of fat and period of time. It was concluded that the effect of ethanol on vitamin status depended on the kind of fat in animals diets.