Fox R A, Daunton N G
Aviat Space Environ Med. 1982 Mar;53(3):218-20.
Conditioned feeding suppression was produced in rats by earth-vertical rotation, seesaw acceleration, and cross-coupled accelerations. Rats were exposed to 15 min of motion immediately after eating a sweet, novel food. The effects of this motion were assessed by measuring consumption of sweet food during a second feeding session that was 72 hr after exposure to motion Exposure to cross-coupled accelerations produced the greatest conditioned suppression of feeding. Progressively less suppression resulted from exposure to seesaw acceleration and to rotation. This ordering of suppression effects is consistent with the amount of vestibular stimulation produced by these motions. These results indicate that conditioned feeding suppression in rats can be produced by vestibular stimulation of a duration known to produce frank motion sickness in other animals and man.
通过地球垂直旋转、跷跷板加速和交叉耦合加速在大鼠中产生条件性摄食抑制。大鼠在食用一种甜的新食物后立即暴露于15分钟的运动中。通过测量在暴露于运动72小时后的第二次喂食期间甜食物的消耗量来评估这种运动的效果。暴露于交叉耦合加速产生了最大程度的条件性摄食抑制。暴露于跷跷板加速和旋转产生的抑制作用逐渐减弱。这种抑制作用的排序与这些运动产生的前庭刺激量一致。这些结果表明，在大鼠中，条件性摄食抑制可由前庭刺激产生，这种刺激的持续时间在其他动物和人类中已知会导致明显的晕动病。
