主动脉胆固醇酯酶。胆汁盐的影响。
Aortic cholesteryl esterase. Influence of bile salts.
作者信息
Kothari H V, Kritchevsky D
出版信息
Atherosclerosis. 1978 Nov;31(3):371-5. doi: 10.1016/0021-9150(78)90072-2.
PMID:718740
Abstract
The in vitro activity of cholesteryl ester hydrolase preparations of rat and rabbit aortas was assayed in the presence of the taurine and glycine conjugates of cholic, chenodeoxycholic, deoxycholic and lithocholic acids or in the presence of Triton X-100 and Tween-20. Maximum activity was obtained with tauro- or glycocholic acids. As in the case of pancreatic cholesteryl esterase, trihydroxycholanoic acid derivatives may serve an obligatory function.
摘要
在胆酸、鹅去氧胆酸、脱氧胆酸和石胆酸的牛磺酸和甘氨酸共轭物存在下，或在Triton X - 100和吐温20存在下，测定大鼠和兔主动脉胆固醇酯水解酶制剂的体外活性。牛磺胆酸或甘氨胆酸可获得最大活性。与胰腺胆固醇酯酶的情况一样，三羟基胆烷酸衍生物可能起重要作用。
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