Heneghan C P, Findley I L, Gillbe C E, Feldman S A
Br J Anaesth. 1978 Nov;50(11):1105-8. doi: 10.1093/bja/50.11.1105.
The effect of changes in muscle blood flow on the rate of recovery from neuromuscular block produced by pancuronium was investigated in dogs, and were shown to be independent variables. The significance of this finding in relation to recent work on blood concentrations of the drug and on the pharmacodynamics of the drug is discussed.
在犬类动物中研究了肌肉血流变化对泮库溴铵所致神经肌肉阻滞恢复速率的影响,结果表明它们是独立变量。文中讨论了这一发现与近期关于该药物血药浓度及药效学研究的相关性。