海兔素A和B在体外及感染裂谷热的小鼠体内对RNA病毒的抑制作用
Inhibition of RNA viruses in vitro and in Rift Valley fever-infected mice by didemnins A and B.
作者信息
Canonico P G, Pannier W L, Huggins J W, Rienehart K L
出版信息
Antimicrob Agents Chemother. 1982 Oct;22(4):696-7. doi: 10.1128/AAC.22.4.696.
Abstract
Didemnins, a new class of depsipeptides isolated from a Caribbean tunicate, have been shown to have potent antiviral activity against a broad range of RNA viruses in vitro. Didemnins A and B both protected mice against a lethal challenge of Rift Valley fever virus.
摘要
地棘蛙素是从一种加勒比被囊动物中分离出的一类新型缩肽，已证明其在体外对多种RNA病毒具有强大的抗病毒活性。地棘蛙素A和B都能保护小鼠免受裂谷热病毒的致命攻击。
相似文献
1
Inhibition of RNA viruses in vitro and in Rift Valley fever-infected mice by didemnins A and B.海兔素A和B在体外及感染裂谷热的小鼠体内对RNA病毒的抑制作用
Antimicrob Agents Chemother. 1982 Oct;22(4):696-7. doi: 10.1128/AAC.22.4.696.
2
Didemnins: antiviral and antitumor depsipeptides from a caribbean tunicate.
Science. 1981 May 22;212(4497):933-5. doi: 10.1126/science.7233187.
3
Antiviral efficacy of pyrazofurin against selected RNA viruses.
Antiviral Res. 1982 Dec;2(6):331-7. doi: 10.1016/0166-3542(82)90002-x.
4
Antiviral (RNA) activity of selected Amaryllidaceae isoquinoline constituents and synthesis of related substances.
J Nat Prod. 1992 Nov;55(11):1569-81. doi: 10.1021/np50089a003.
5
Antiviral and antitumor compounds from tunicates.来自被囊动物的抗病毒和抗肿瘤化合物。
Fed Proc. 1983 Jan;42(1):87-90.
6
Structure--activity relationships of the didemnins.海鞘素的构效关系。
J Med Chem. 1996 Jul 5;39(14):2819-34. doi: 10.1021/jm960048g.
7
Anti-Rift Valley fever virus activity in vitro, pre-clinical pharmacokinetics and oral bioavailability of benzavir-2, a broad-acting antiviral compound.体外抗裂谷热病毒活性、广谱抗病毒化合物苯扎韦-2 的临床前药代动力学和口服生物利用度。
Sci Rep. 2018 Jan 31;8(1):1925. doi: 10.1038/s41598-018-20362-9.
8
Identification and evaluation of antivirals for Rift Valley fever virus.裂谷热病毒抗病毒药物的鉴定和评估。
Vet Microbiol. 2019 Mar;230:110-116. doi: 10.1016/j.vetmic.2019.01.027. Epub 2019 Jan 29.
9
Galidesivir limits Rift Valley fever virus infection and disease in Syrian golden hamsters.加力迪昔韦能限制裂谷热病毒在叙利亚金黄地鼠中的感染和疾病。
Antiviral Res. 2018 Aug;156:38-45. doi: 10.1016/j.antiviral.2018.05.013. Epub 2018 Jun 1.
10
Protein Phosphatase-1 regulates Rift Valley fever virus replication.蛋白磷酸酶-1调节裂谷热病毒的复制。
Antiviral Res. 2016 Mar;127:79-89. doi: 10.1016/j.antiviral.2016.01.007. Epub 2016 Jan 20.
引用本文的文献
1
Promising bioactive compounds from the marine environment and their potential effects on various diseases.来自海洋环境的有前景的生物活性化合物及其对各种疾病的潜在影响。
J Genet Eng Biotechnol. 2022 Jan 26;20(1):14. doi: 10.1186/s43141-021-00290-4.
2
Marine Natural Products from Tunicates and Their Associated Microbes.海洋被囊动物及其共生微生物来源的天然产物。
Mar Drugs. 2021 May 26;19(6):308. doi: 10.3390/md19060308.
3
Potential "biopeptidal" therapeutics for severe respiratory syndrome coronaviruses: a review of antiviral peptides, viral mechanisms, and prospective needs.严重呼吸综合征冠状病毒的潜在“生物肽”治疗方法：抗病毒肽、病毒机制及预期需求的综述。
Appl Microbiol Biotechnol. 2021 May;105(9):3457-3470. doi: 10.1007/s00253-021-11267-1. Epub 2021 Apr 19.
4
Marine natural products and their potential applications as anti-infective agents.海洋天然产物及其作为抗感染剂的潜在应用。
Lancet Infect Dis. 2003 Jun;3(6):338-48. doi: 10.1016/s1473-3099(03)00655-8.
5
Didemnin B. The first marine compound entering clinical trials as an antineoplastic agent.地棘蛙素B。第一种作为抗肿瘤药物进入临床试验的海洋化合物。
Invest New Drugs. 1986;4(3):279-84. doi: 10.1007/BF00179597.
本文引用的文献
1
Didemnins: antiviral and antitumor depsipeptides from a caribbean tunicate.
Science. 1981 May 22;212(4497):933-5. doi: 10.1126/science.7233187.
Zotero 插件