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神经突变小鼠浦肯野细胞变性(PCD)中的二尖瓣细胞变性与感觉功能

Mitral cell degeneration and sensory function in the neurological mutant mouse Purkinje cell degeneration (PCD).

作者信息

Greer C A, Shepherd G M

出版信息

Brain Res. 1982 Mar 4;235(1):156-61. doi: 10.1016/0006-8993(82)90206-2.

DOI:10.1016/0006-8993(82)90206-2
PMID:7188319
Abstract

Selective degeneration of mitral cells, the principal relay neuron in the central olfactory pathway, is described in the mutant mouse Purkinje cell degeneration (PCD). Concomitant effects are described in adjacent layers of the olfactory bulb which suggest a reorganization of local neuronal circuits. The 2-deoxyglucose technique produced results which suggested that the topographical distribution of sensory afferent input to the bulb was not affected.

摘要

在突变小鼠浦肯野细胞变性(PCD)中,描述了中枢嗅觉通路中的主要中继神经元——二尖瓣细胞的选择性变性。嗅球相邻层出现了相应的影响,这表明局部神经元回路发生了重组。2-脱氧葡萄糖技术产生的结果表明,传入嗅球的感觉传入输入的拓扑分布未受影响。

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