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[闭经-溢乳综合征。5例治疗病例的临床与治疗方面]

[The amenorrhea-galactorrhea syndrome. Clinical and therapeutic aspects of 5 treated cases].

作者信息

Nicoletti I, Filipponi P, Nunzi E, Angeletti G, Santeusanio F

出版信息

Minerva Med. 1980 Jan 21;71(2):89-96.

PMID:7188809
Abstract

The behaviour of plasma prolactin in response to various pharmacological tests has been examined together with that of other hypophyseal function parameters in five patients suffering from amenorrhoea-galactorrhoea syndrome. Evaluation of plasma prolactin and hypophyseal tropinic reserve levels did not prove sufficient to discriminate between functional and organic forms of hyperprolactinaemia. A woman patient was submitted to neurosurgical operation for removal of a hypophyseal microadenoma. The other patients were treated medically with 2-alpha-bromoergocryptin which produced quick normalization of prolactinaemia with restoration of normal memstrual cycles and cessation of galactorrhoea.

摘要

对五名患有闭经-溢乳综合征的患者,研究了血浆催乳素对各种药理试验的反应,并与其他垂体功能参数的反应进行了比较。评估血浆催乳素和垂体促性腺激素储备水平不足以区分功能性和器质性高催乳素血症。一名女性患者接受了神经外科手术以切除垂体微腺瘤。其他患者接受了2-α-溴麦角隐亭药物治疗,该药物使催乳素血症迅速恢复正常,月经周期恢复正常,溢乳停止。

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