Finelli P F, McEntee W J, Ambler M, Kestenbaum D
Neurology. 1980 Mar;30(3):245-9. doi: 10.1212/wnl.30.3.245.
A progressive pancerebellar syndrome in a 57-year-old man heralded what was subsequently diagnosed by malabsorption studies and jejunal biopsy as adult celiac disease. Postmortem examination demonstrated characteristic gastrointestinal and cerebral abnormalities associated with this enteropathy. The neuropathology underlying the ataxia, as well as the clinical features of palatal myoclonus and marked speech impairment, included marked cerebellar cortical atrophy with cell loss in dentate and olivary nuclei. Intestinal-absorption studies are indicated to evaluate patients with any neurologic illness that may be related to malabsorption.
一名57岁男性出现进行性小脑综合征，随后经吸收不良研究和空肠活检诊断为成人乳糜泻。尸检显示了与这种肠病相关的典型胃肠道和脑部异常。共济失调、腭肌阵挛和明显言语障碍的神经病理学表现包括小脑皮质明显萎缩，齿状核和橄榄核细胞丢失。对于任何可能与吸收不良有关的神经系统疾病患者，均建议进行肠道吸收研究。
