Barrie K P, Gelatt K N, Gwin R M, Peiffer R L
Am J Vet Res. 1980 Jan;41(1):51-4.
The base and pupillary zones of the iris were exposed for 10 s to a -79 C cryoprobe (iridocryothermy). The resultant iritis lasted 7 to 10 days as evidenced by aqueous flare, hypotony, and miosis. At 21 days, the iris was depigmented and had an irregular pupil. The initial histopathologic changes after iridocryothermy were iridic intrastromal hemorrhage, exudation, and neutrophil infiltration. The iridic pigmented epithelium was lyzed, and the melanin granules were liberated into the iridic stroma, posterior, and anterior chambers. Irides frozen at the pupillary zone exhibited sphincter muscle degeneration. By 21 days after iridocryothermy, the irides were depigmented and atrophic.
将虹膜的基部和瞳孔区暴露于-79℃的冷冻探头下10秒（虹膜冷冻术）。由此产生的虹膜炎持续7至10天，表现为房水闪光、低眼压和瞳孔缩小。21天时，虹膜色素脱失，瞳孔不规则。虹膜冷冻术后最初的组织病理学变化为虹膜基质内出血、渗出和中性粒细胞浸润。虹膜色素上皮溶解，黑色素颗粒释放到虹膜基质、后房和前房。在瞳孔区冷冻的虹膜显示括约肌肌肉变性。虹膜冷冻术后21天时，虹膜色素脱失且萎缩。
