Neil J F, Holzer B C, Spiker D G, Coble P A, Kupfer D J
Neurology. 1980 Jun;30(6):660-2. doi: 10.1212/wnl.30.6.660.
All-night polygraphic recordings of the electroencephalogram, horizontal electrooculogram, and submental electromyogram were performed in two patients with familial olivopontocerebellar degeneration. Sleep was characterized by subnormal measurements of both rapid eye movement (REM) and delta (slow-wave) sleep. Phasic eye movements were reduced out of proportion to tonic components of REM sleep. These findings lend further support to theories linking the pontine nuclei to the primary regulation of sleep in both experimental animals and humans.
对两名患有家族性橄榄体脑桥小脑萎缩的患者进行了脑电图、水平眼电图和颏下肌电图的整夜多导记录。睡眠的特征是快速眼动(REM)睡眠和δ(慢波)睡眠的测量值均低于正常水平。与REM睡眠的紧张性成分相比,眼球的快速运动减少得更为明显。这些发现进一步支持了在实验动物和人类中,将脑桥核与睡眠的主要调节联系起来的理论。