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[Changes in ultrastructural synaptoarchitectonics induced by endotoxin].

作者信息

Bardakhch'ian E A, Saakov B A

出版信息

Biull Eksp Biol Med. 1978 Nov;86(11):610-3.

PMID:719158
Abstract

The authors studied the ultrastructure of synapses of the dog sensory-motor cortex in response to intravenous injection of typhoid endotoxin. The most pronounced shifts were noted in the dendrite neuron apparatus. Activation in the cortical structures was connected with an increase in the number of functioning synapses and reconstruction of interneuronal connections. There was an increase in the length of the contacting membranes, and of the quantity of synaptic vesicles; the content of dense core vesicles is released. Depression is associated with dystrophic changes in the synapses.

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