Yagi T, Ishizaki K, Takebe H
Cancer Lett. 1980 Oct;10(4):301-7. doi: 10.1016/0304-3835(80)90046-4.
Effects of elastatinal, a protease inhibitor, on DNA repair and its cytotoxicity were investigated in normal human, xeroderma pigmentosum and Chinese hamster V79 cells. There were no effects of elastatinal on DNA repair and UV-induced sister chromatid exchanges, and all 3 cell lines demonstrated essentially the same sensitivity to the cytotoxic effect of elastatinal. These results were quite different from those by antipain, another protease inhibitor, and caffeine.
在正常人、着色性干皮病患者和中国仓鼠V79细胞中研究了蛋白酶抑制剂弹性蛋白酶抑制剂对DNA修复及其细胞毒性的影响。弹性蛋白酶抑制剂对DNA修复和紫外线诱导的姐妹染色单体交换没有影响，并且所有3种细胞系对弹性蛋白酶抑制剂的细胞毒性表现出基本相同的敏感性。这些结果与另一种蛋白酶抑制剂抗蛋白酶和咖啡因的结果有很大不同。
