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用抗抑郁药治疗的实验性抑郁犬脊髓反射的肌电图评估

Electromyographic assessment of spinal reflexes in experimentally depressed dogs treated with antidepressants.

作者信息

Fonberg E, Kasicki S, Korczyński R

出版信息

Acta Neurobiol Exp (Wars). 1980;40(3):651-63.

PMID:7192046
Abstract

In seven mongrel dogs the syndrome of depression was evoked by bilateral electrolytic lesions in lateral hypothalamus and/or dorsomedial amygdala. The effects of tricyclic antidepressants on general mood, spinal reflexes recorded by electromyographic method, and head rate were tested. The reactivity to most external stimuli was increased and general depression was slightly reduced.

摘要

在7只杂种狗中,通过双侧电解损伤下丘脑外侧和/或杏仁核背内侧诱发抑郁综合征。测试了三环类抗抑郁药对总体情绪、通过肌电图记录的脊髓反射以及心率的影响。对大多数外部刺激的反应性增加,总体抑郁略有减轻。

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