Papasozomenos S, Roessmann U
Neurology. 1981 Jan;31(1):97-100. doi: 10.1212/wnl.31.1.97.
Fourteen children with Arnold-Chiari malformation had history of respiratory distress, apnea, vocal cord paralysis or inability to swallow. Postmortem examination in 12 disclosed vascular lesions in the tegmentum of the medulla oblongata. The length of survival of these children was markedly shorter than of those without such history and anatomic findings. It is suggested that the malformation results in changes in the vascular supply of the herniated portion of the brainstem. Stretching of the arteries may result in irreversible damage to the brainstem with subsequent life-threatening disturbance of respiratory function.
14名患有阿诺德-奇阿利畸形的儿童有呼吸窘迫、呼吸暂停、声带麻痹或吞咽困难的病史。12例尸检显示延髓被盖部有血管病变。这些儿童的存活时间明显短于没有此类病史和解剖学发现的儿童。提示该畸形导致脑干疝出部分的血管供应发生改变。动脉的拉伸可能导致脑干不可逆转的损伤，继而引发危及生命的呼吸功能紊乱。
