Schiff J D, Overweg N I
Pflugers Arch. 1980 Dec;389(1):75-9. doi: 10.1007/BF00587931.
The effects of changing bathing medium osmolality on tension generation in smooth muscle were studied on potassium-depolarized segments of rat ileum. Increasing the tonicity of the medium evokes a transient relaxation of the smooth muscle; restoration of isotonicity evokes a transient contraction of similar amplitude and time course. While immersed in hypertonic media of less than 1.3 times normal tonicity, the smooth muscle slowly increases its isometric tension; in media of nearly twice normal tonicity, the smooth muscle loses tension. All of these effects occur whether the medium is made hypertonic with added NaCl or sucrose.
在大鼠回肠的钾去极化节段上研究了改变浴液渗透压对平滑肌张力产生的影响。增加浴液的张力会引起平滑肌的短暂松弛；恢复等渗会引起幅度和时程相似的短暂收缩。当浸入渗透压小于正常渗透压1.3倍的高渗溶液中时，平滑肌会缓慢增加其等长张力；在渗透压接近正常渗透压两倍的溶液中，平滑肌会失去张力。无论浴液是用添加的氯化钠还是蔗糖制成高渗溶液，所有这些效应都会发生。
