Rottmann O J, Lampeter W W
J Reprod Fertil. 1981 Mar;61(2):303-6. doi: 10.1530/jrf.0.0610303.
Criteria for assessing embryo vitality of denuded rabbit and mouse embryos in vitro were: volume of the embryo, number of cells and number of metaphase plates after 24 and 48 h in culture. Mouse embryos grew normally, with and without the zona pellucida, but denuded rabbit embryos showed reduced growth (volume and cell number) and failure to implant in synchronized recipients.