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某些真菌分离株代谢产物对瑞士白化小鼠产生的霉菌毒素中毒的组织病理学

Histopathology of Mycotoxicosis produced in Swiss albino mice by metabolites of some fungal isolates.

作者信息

Gupta J, Pathak B, Sethi N, Vora V C

出版信息

Appl Environ Microbiol. 1981 Mar;41(3):752-7. doi: 10.1128/aem.41.3.752-757.1981.

Abstract

Of 199 fungal cultures isolated from some of the common cereals collected from different parts of Uttar Pradesh and Madhya Pradesh, 70 produced toxic metabolites. Of the 70 fungi isolated, 59 produced toxins which caused visible lesions in livers, kidneys, and spleens but did not cause mortality. Toxicity, graded in terms of the mortality rate and the extent of lesions in livers, kidneys, and spleens, was found to be highest in various species of Aspergillus (40%), followed by Chaetomium spp. (31%).

摘要

从北方邦和中央邦不同地区采集的一些常见谷物中分离出199种真菌培养物,其中70种产生了有毒代谢物。在分离出的70种真菌中,59种产生的毒素会在肝脏、肾脏和脾脏中造成可见损伤,但不会导致死亡。根据死亡率以及肝脏、肾脏和脾脏中的损伤程度进行分级,发现曲霉属的各种真菌毒性最高(40%),其次是毛壳菌属(31%)。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9f0b/243771/f6dd573f4716/aem00196-0206-a.jpg

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