婴儿期从“正常”左心室流出道迅速演变为致命的主动脉瓣下狭窄。

Freedom R M, Fowler R S, Duncan W J

Br Heart J. 1981 May;45(5):605-9. doi: 10.1136/hrt.45.5.605.

Serial clinical, echocardiographic, haemodynamic, and angiocardiographic data support the conclusion that over four months severe discrete subaortic stenosis evolved from a previously angiocardiographically normal left ventricular outflow tract in an infant who had a successful repair of thoracic aortic coarctation. This case supports those who suggest that a myocardial factor may play an important role in the change in form and function of some congenitally malformed hearts.

一系列临床、超声心动图、血流动力学和心血管造影数据支持以下结论：一名成功修复胸主动脉缩窄的婴儿，在四个多月的时间里，严重的局限性主动脉瓣下狭窄从先前心血管造影正常的左心室流出道演变而来。该病例支持了那些认为心肌因素可能在一些先天性畸形心脏的形态和功能变化中起重要作用的观点。