Corruccini R S, Potter R H
Am J Phys Anthropol. 1981 May;55(1):21-31. doi: 10.1002/ajpa.1330550105.
To improve our understanding of dental asymmetry, more anatomically discriminating measurements than maximum crown dimensions were used. The relation between antimeres and opponents in permanent first molar teeth of 192 twins were studied with respect to crown components measures. Several statistical methods were used to describe asymmetry and discrepancy of occluding units to correlate with developmental stress indicators such as zygosity, birth weight, and congenital disease. To varying degrees, developmental correlates are found to be associated with asymmetry. The amount of occlusal discrepancy seems to be a direct function of bilateral asymmetry. Heterogeneity of MZ-DZ total (among plus within pair) variances occurs fairly consistently for asymmetry but not for discrepancy, implying differential environmental influences between zygosities regarding asymmetry. Genetic variance estimates, designed to be unbiased by differences in environmental variances, are significant for cusp size but not for asymmetry. Our results suggest that asymmetry at the individual cusp level may be an indicator of developmental disruption and that environmental effects, particularly prenatal, may be greater for antimeric units than for occluding units.
为了增进我们对牙齿不对称性的理解，我们采用了比最大牙冠尺寸更具解剖学区分度的测量方法。针对192对双胞胎的恒牙第一磨牙，研究了其镜像牙与对颌牙之间在牙冠各部分测量指标上的关系。运用了多种统计方法来描述咬合单位的不对称性和差异，以便与诸如合子性、出生体重和先天性疾病等发育应激指标相关联。在不同程度上，发现发育相关因素与不对称性有关。咬合差异的程度似乎是双侧不对称性的直接函数。同卵双胞胎 - 异卵双胞胎总体（双胞胎对内和双胞胎对间）方差的异质性在不对称性方面相当一致地出现，但在差异方面则不然，这意味着在不对称性方面，不同合子性之间存在不同的环境影响。旨在不受环境方差差异影响的遗传方差估计，对于牙尖大小具有显著性，但对于不对称性则不然。我们的结果表明，单个牙尖水平的不对称性可能是发育紊乱的一个指标，并且环境影响，尤其是产前环境影响，对于镜像牙单位可能比对咬合单位更大。
