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感染方式对大鼠微小膜壳绦虫发育及化疗反应的影响。

Effect of mode of infection on the development and chemotherapeutic response of Hymenolepis nana in rats.

作者信息

Gupta S, Katiyar J C, Sen A B

出版信息

J Helminthol. 1981 Jun;55(2):101-7.

PMID:7196424
Abstract

The susceptibility of rats to Hymenolepis nana (Cestoda) and the chemotherapeutic response of anti-cestode drugs was studied during egg-inducted and cysticercoid-induced infections. In cysticercoid-induced infection, the percentage of infected animals and the number of mature worms were significantly more than in egg-induced infection. The former mode of transmission required more drug to clear the parasites. These differences have been discussed on the basis of immunity engendered in the definitive host by the developing larvae.

摘要

研究了大鼠对微小膜壳绦虫(绦虫纲)的易感性以及抗绦虫药物在虫卵诱导感染和似囊尾蚴诱导感染期间的化疗反应。在似囊尾蚴诱导的感染中,受感染动物的百分比和成熟虫体的数量显著多于虫卵诱导的感染。前一种传播方式需要更多药物来清除寄生虫。已根据发育中的幼虫在终末宿主体内产生的免疫力对这些差异进行了讨论。

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J Helminthol. 1981 Jun;55(2):101-7.
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