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老年患者膀胱黏膜的化生与增殖过程(作者译)

[Metaplastic and proliferative processes of the bladder mucosa in elderly patients (author's transl)].

作者信息

Schubert G E, Pavković M, Kirchhoff L

出版信息

Urologe A. 1981 Jul;20(4):196-203.

PMID:7196629
Abstract

The frequency of 20 morphological findings in bladders fixed shortly after death obtained at post mortem examination from an unselected nonurological series of 70 patients with a median age of 74 years, we studied by evaluation of 12 600 histological data. Squamous metaplasia was found in 27.8% of male and 82.2% of female subjects predominantly at the bladder neck and floor. Squamous metaplasia with different structures at the posterior and lateral wall showed a preponderance in the male subjects. Brunn's nests were observed in 88.9% of male and 88.2% of female patients, sometimes as "Brunn's nests in situ". Focal urothelial hyperplasia was seen in 41.7% of male and 38.2% of female, "labile epithelium" in 13.9% of male and 29.4+ female, micropapillomas in 13.9% male and 11.8% female patients. One male subject (72 years old) had an urothelial carcinoma measuring 1.2 cm (G-2-pT1) which was not recognised clinically.

摘要

在一项对70例未经选择的非泌尿系统疾病患者(中位年龄74岁)进行的尸检研究中,我们通过评估12600份组织学数据,研究了死后不久固定的膀胱中20种形态学表现的发生频率。鳞状化生在男性受试者中占27.8%,在女性受试者中占82.2%,主要发生在膀胱颈和底部。后壁和侧壁具有不同结构的鳞状化生在男性受试者中更为常见。在88.9%的男性和88.2%的女性患者中观察到布伦巢,有时表现为“原位布伦巢”。局灶性尿路上皮增生在41.7%的男性和38.2%的女性中可见,“不稳定上皮”在13.9%的男性和29.4%的女性中可见,微乳头状瘤在13.9%的男性和11.8%的女性患者中可见。一名男性受试者(72岁)患有1.2厘米大小的尿路上皮癌(G-2-pT1),临床未识别出来。

相似文献

1
[Metaplastic and proliferative processes of the bladder mucosa in elderly patients (author's transl)].老年患者膀胱黏膜的化生与增殖过程(作者译)
Urologe A. 1981 Jul;20(4):196-203.
2
Epithelial abnormalities of urinary bladder.膀胱上皮异常
Prog Clin Biol Res. 1984;162A:81-93.
3
NTP Toxicology and Carcinogenesis Studies of 1-Amino-2,4-Dibromoanthraquinone (CAS No. 81-49-2) in F344/N Rats and B6C3F1 Mice (Feed Studies).1-氨基-2,4-二溴蒽醌(CAS编号:81-49-2)在F344/N大鼠和B6C3F1小鼠中的NTP毒理学与致癌性研究(饲料喂养研究)
Natl Toxicol Program Tech Rep Ser. 1996 Aug;383:1-370.
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Epithelial lesions of the urinary bladder in three hundred and thirteen autopsy cases.313例尸检病例中膀胱的上皮性病变
Jpn J Cancer Res. 1987 Oct;78(10):1073-80.
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[Hyperplastic-proliferative and preneoplastic lesions of the bladder urothelium (author's transl)].膀胱尿路上皮的增生性-增殖性和癌前病变(作者译)
Pathologica. 1981 Jul-Aug;73(1026):597-612.
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Noninvasive squamous lesions in the urinary bladder: a clinicopathologic analysis of 29 cases.膀胱非侵袭性鳞状病变:29例临床病理分析
Am J Surg Pathol. 2006 Jul;30(7):883-91. doi: 10.1097/01.pas.0000213283.20166.5a.
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The prevalence and significance of Brunn's nests, cystitis cystica and squamous metaplasia in normal bladders.正常膀胱中布伦巢、囊性膀胱炎和鳞状化生的发生率及意义。
J Urol. 1979 Sep;122(3):317-21. doi: 10.1016/s0022-5347(17)56384-3.
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Morphologic classification of inflammatory, nonspecific, and proliferative lesions of the urinary bladder of mice.小鼠膀胱炎症性、非特异性和增殖性病变的形态学分类
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[Precancerous importance of chronic cystitis and papilloma of the bladder].[慢性膀胱炎和膀胱乳头状瘤的癌前重要性]
Arkh Patol. 1988;50(10):27-32.
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The prevalence and distribution of proliferative and metaplastic changes in normal appearing canine bladders.正常外观犬膀胱中增生性和化生改变的患病率及分布情况。
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