Burden H W, Lawrence I E, Louis T M, Hodson C A
Neuroendocrinology. 1981;33(4):218-22. doi: 10.1159/000123232.
Abdominal vagotomy of estrus or proestrus rats resulted in disruptions of the estrous cycle which was characterized by prolonged periods of diestrus (10-12 days in length). In contrast, vagotomy on metestrus or diestrus did not disrupt the estrous cycle. The induction of pseudopregnancy, in response to cervical stimulation on the morning of estrus, was also interrupted by abdominal vagotomy. The nocturnal and diurnal prolactin surges and elevations in serum progesterone, characteristic of pseudopregnancy, were prevented by vagotomy. Vagotomy, also, largely prevented the formation of deciduoma in response to traumatization of the uterus in cervically stimulated rats.
对处于发情期或发情前期的大鼠进行腹部迷走神经切断术，会导致发情周期紊乱，其特征为动情间期延长（长达10 - 12天）。相比之下，在间情期或动情后期进行迷走神经切断术不会扰乱发情周期。在发情期早晨对子宫颈进行刺激所诱导的假孕，也会因腹部迷走神经切断术而中断。迷走神经切断术可阻止假孕所特有的夜间和白天催乳素激增以及血清孕酮升高。迷走神经切断术在很大程度上还可防止经子宫颈刺激的大鼠子宫受创伤后蜕膜瘤的形成。
