Gehrig J D, Colpitts Y H, Chapman C R
Anesth Analg. 1981 Nov;60(11):779-82.
The effects of lidocaine 2% infiltration on the brain-evoked potential elicited by painful dental stimulation were observed in human subjects. Both the evoked potential wave form and the subjective pain were eliminated by the local anesthetic in 10 volunteers, whereas saline infiltration under identical conditions in 10 others had no effect. These results support our other observations which indicate that brain-evoked potentials recorded during painful dental stimulation are a reliable physiologic correlate of human pain.
在人体受试者中观察了2%利多卡因浸润对牙科疼痛刺激诱发的脑诱发电位的影响。10名志愿者中，局部麻醉剂消除了诱发电位波形和主观疼痛，而在另外10名受试者相同条件下进行的生理盐水浸润则没有效果。这些结果支持了我们的其他观察结果，即牙科疼痛刺激期间记录的脑诱发电位是人类疼痛可靠的生理相关指标。
