Shapiro L A, Hoffman S, Jedeikin R, Kaplan R
Anesth Analg. 1981 Nov;60(11):818-20.
In 30 patients having prostatectomies, 15 patients (group I) given single-injection epidural anesthesia using bupivacaine and morphine (4 mg) were compared with 15 patients (group II) given epidural bupivacaine without morphine. Patients in group I had pain relief for a mean duration of 27 hours and did not request additional analgesia. Patients receiving bupivacaine alone had pain relief for an average of 6.2 hours after surgery; all required narcotics postoperatively. It was concluded that the addition of 4 mg of morphine to the local anesthetic for epidural anesthesia in patients having prostatectomies results in excellent postoperative analgesia.
在30例行前列腺切除术的患者中，将15例使用布比卡因和吗啡（4毫克）进行单次硬膜外麻醉的患者（第一组）与15例仅使用布比卡因硬膜外麻醉的患者（第二组）进行比较。第一组患者的疼痛缓解平均持续时间为27小时，且未要求额外镇痛。仅接受布比卡因的患者术后平均疼痛缓解时间为6.2小时；所有患者术后均需要使用麻醉剂。得出的结论是，在接受前列腺切除术的患者的硬膜外麻醉局部麻醉剂中添加4毫克吗啡可产生出色的术后镇痛效果。
