Carel R S, Shapiro M S, Shoham D, Gutman A
Chest. 1977 Nov;72(5):670-2. doi: 10.1378/chest.72.5.670.
A 63-year-old man developed an asymptomatic pleural effusion following the administration of 500 gm of procainamide hydrochloride over a six-month period. The diagnosis was initially suggested by the finding of lupus erythematosus cells in the pleural fluid. Lupus erythematosus cells and antinuclear antibodies appeared in the blood two months later and remained for a period of six months. The diagnosis was corroborated by the presence of antibodies to denatured DNA, but not to native DNA.
一名63岁男性在6个月内服用了500克盐酸普鲁卡因胺后出现无症状性胸腔积液。胸腔积液中发现红斑狼疮细胞最初提示了诊断。两个月后血液中出现了红斑狼疮细胞和抗核抗体，并持续了6个月。抗变性DNA而非天然DNA抗体的存在证实了诊断。
